In the pharmaceutical industry, ensuring the quality and safety of products is imperative. A problem common to many companies is the presence of harmful endotoxins in medicinal fluids. These endotoxins, derived from bacterial cell walls, can have serious consequences for both the effectiveness of the medicine and the health of patients. This report highlights a specific case where a customer was experiencing elevated levels of endotoxins, which rendered their medicine unusable. Through thorough research and testing, we found an effective solution that not only addressed the problem, but also ensured the client's operational continuity.
Client problem: Endotoxins
Our client experienced significant problems because their medicinal liquid contained too many endotoxins. This excess rendered the product unusable, leading to production interruptions and a drop in product quality. The challenge was to find a solution that could effectively reduce the endotoxins without affecting the integrity of the product. In this, pharmacies also play an important role in providing reliable information about drugs and treatments, which has implications in patients' health.
What are Endotoxins?
Endotoxins are toxic substances released from the cell walls of certain gram-negative bacteria. The presence of endotoxins in pharmaceutical products poses a serious risk as they can lead to adverse reactions in the human body and quality problems in medicinal liquids.
Test phases
To address the problem effectively, we started by conducting several phases of testing at customer sites. These tests focused on identifying filtration technologies capable of reducing the level of endotoxins in the liquid. After extensive evaluation and analysis, we concluded that the VBUNAF-END-20-EGS filter offered the most suitable solution. This filter proved capable of significantly reducing endotoxin levels, allowing the medicinal liquid to be safely used for production again.
Product The VBUNAF filter media combines innovative technology with high-quality materials for optimal filtration. Made from a unique blend of borosilicate glass fibers and Nano Alumina fibers, this non-woven structure offers an exceptionally high positive zeta potential of over 50 mV. This ensures a powerful electrostatic attraction ideal for removing negatively charged contaminants such as endotoxins and Legionella bacteria. The filter media is not only efficient but also durable. It has excellent flow rates and generates low pressure drops, reducing operational costs. Furthermore, the VBUNAF has been tested and approved for use in various applications, including water treatment and disinfection systems. Click on the product to go to the product page! ⇒VBUNAF
Development conclusion
The implementation of the VBUNAF-END-20-EGS filter not only solved the problem of elevated endotoxins, but also ensured improved quality and safety of the finished products. This allows the customer to resume their production process with the peace of mind that the medicinal liquids meet strict quality standards. This case shows how important the right filtration technology can be in the pharmaceutical industry, where patient health and product integrity are paramount. By proactively looking for solutions, the impact of endotoxins can be significantly reduced, ultimately leading to a more reliable and safer end product.
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